Protein Molecular Weight Markers
ABclonal Technology SEMA4F Rabbit pAb
This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.
ABclonal Technology SUGP2 Rabbit pAb
This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described.
Takara Bio YEAST MAKER TRANSFORMATN SYST
Yeastmaker Yeast Transformation System, For use with all yeast-based Matchmaker systems, Can be used for any plasmid transformation, 100 small scale transformations
ABclonal Technology PPP6C Rabbit mAb
This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.
ABclonal Technology LEF1 Rabbit pAb
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
ABclonal Technology Phospho-PPP1R12A/PPP1R12B/PPP1R12C-T696 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a subunit of myosin phosphatase, which regulates actin-myosin interactions via Rho, a small GTPase. RhoA, in its GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, affecting smooth muscle contraction and nonmuscle cell function. Rho-kinase, activated by GTP-RhoA, phosphorylates MBS, inhibiting myosin phosphatase. Overexpression or activation of RhoA increases MBS and MLC phosphorylation. MBS plays a critical role in modulating actin-myosin interactions and is regulated by RhoA signaling. Several isoforms of this gene arise from alternative splicing.
ABclonal Technology HOOK3 Rabbit pAb
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.
ABclonal Technology DCAF7 Rabbit mAb
This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.
Biotang Inc Prestained Protein Marker (10-240 Kda),Three color bands(Green, Blue, Red). Ready-to-Use no need to boil.Broad range size estimation(11-240kDa). Highly purified and blended 11 recombinant proteins 2x250ul. Store at 2-8 deg.C
Prestained Protein Marker (10-240 Kda),Three color bands(Green, Blue, Red). Ready-to-Use no need to boil.Broad range size estimation(11-240kDa). Highly purified and blended 11 recombinant proteins 2x250ul. Store at 2-8 deg.C
![ABclonal Technology [KO Validated] PRKAR1A Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000138662.jpg-250.jpg)
ABclonal Technology [KO Validated] PRKAR1A Rabbit pAb
cAMP is a signaling molecule that activates cAMP-dependent protein kinase, which transduces signals through phosphorylation of target proteins. The inactive kinase is a tetramer of two regulatory and two catalytic subunits. cAMP dissociates this holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free catalytic subunits. This gene encodes one of the regulatory subunits and was found to down-regulate liver gene expression in hepatoma-fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). The gene can fuse with the RET protooncogene to form the PTC2 chimeric oncogene in thyroid tumors. A nonconventional nuclear localization sequence suggests its role in DNA replication by transporting the RFC40 subunit. Several splice variants encoding different isoforms have been observed.
Biolegend Purified anti-mouse Podoplanin
Purified anti-mouse Podoplanin Recombinant [QA20A17]; Isotype: Rat IgG1, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
ABclonal Technology PDE1A Rabbit pAb
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109], Fidock et al., 2002 [PubMed 11747989]).
ABclonal Technology TENM1 Rabbit pAb
The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology ASCC1 Rabbit pAb
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
